WebCyclothiazide is a positive allosteric modulator of ionotropic α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptors with critical roles in neurological development and function. CAS No. 2259-96-3 Selleck's Cyclothiazide has been cited by 8 Publications iScience,202425-9:104952 Adv Sci (Weinh),2024e2004846 WebCyclothiazide (CTZ) is an AMPA receptor positive allosteric modulator (PAM) which produces a fast inhibition of AMPAR desensitization and a slow potentiation of the AMPA …
Cyclothiazide - Wikiwand
WebFeb 20, 2024 · Chlorothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Chlorothiazide has also been found useful in … WebOct 19, 2024 · Medicinal Uses. Chlorothiazide is used for: Management of hypertension; Management of edema related to heart failure; For increasing effectiveness of other antihypertensive drugs in severe Side Effects. Side effects of chlorothiazide are: Headache; Lightheadedness; Dizziness; Blurred vision; Spinning feelings; Diarrhea; Constipation; … rcgp women\\u0027s health library
Cyclothiazide - Wikipedia
WebCyclothiazide Chemical Structure CAS NO. 2259-96-3 Cyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptors, positively modulating its response to glutamic acid (EC50 = 3.8 M). Availability: In stock Free Overnight Delivery on orders over $500 Next day delivery by 10:00 a.m. Order now. Add to Cart Bulk Inquiry Price Match WebCyclothiazide was used to prevent desensitization of AMPA-receptors in hippocampal pyramidal neurons. The compound prolonged the decay time of multi-synaptic evoked … WebCyclothiazide Note: Cyclothiazide is a benzothiadiazine diuretic and antihyper- tensive drug structurally related to diazoxide. From:Ion Channel Factsbook: Extracellular Ligand-Gated Channels, 1996 Related terms: Glutamate Modulator Protein Propionic Acid Kainic Acid Diuretic [Alpha] Thiazide Diuretic Agent View all Topics Download as PDF Set alert rcgp women\u0027s health library