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WebAffiliations 1 Sheffield Children's Hospital NHS Foundation Trust, Western Bank, Sheffield, UK.; 2 Clinical Genetics Department, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.; 3 Department of Clinical Genetics, Churchill Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.; 4 Wessex Clinical Genetics Service, University … WebApr 15, 1997 · A number of studies have shown that the CAG repeat number on HD disease chromosomes only accounts for 50–61% of the variance of the age of onset (2–4).The contribution of the CAG repeat number to age of onset is less marked at the lower end of the disease size range and accounts for about 20% of the variance in individuals with fewer … center for gifted studies wku

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