Induction of apoptosis in cancer cells
Web29 jun. 2016 · Indeed, VC-A induced apoptosis in PDA cells as demonstrated by the increased binding of Annexin V and cleavage of PARP-1 and procaspases-3, -8 and -9. These results corroborate the findings of another study that also reported cell cycle arrest and induction of apoptosis in breast cancer cells by VC-A . WebThis in turn led to enhanced apoptosis in the MUC16-knockdown breast cancer cells through Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated extrinsic apoptotic pathway with the help of c-Jun N-terminal kinase signaling.
Induction of apoptosis in cancer cells
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Web30 nov. 2012 · Apoptosis induction by nimbolide treatment was determined by JC-1 mitochondrial membrane potential staining, cytochrome c release, caspase … WebLipopeptide treatment induced extensive DNA damage in the treated cells, which was indicated by a TUNEL assay. Flow cytometric analysis exhibited lipopeptide …
Web20 feb. 2013 · Vernodalin inhibited cell growth of human breast cancer cells MCF-7 and MDA-MB-231 by induction of cell cycle arrest and apoptosis. Increased of reactive oxygen species (ROS) production, coupled with downregulation of anti-apoptotic molecules (Bcl-2, Bcl-xL) led to reduction of mitochondrial membrane potential (MMP) and release of … Web3 mrt. 2024 · Although cumulative evidence has demonstrated the apoptotic effect and cytotoxicity of DHA against tumour development in many cell types, the precise cellular and biochemical mechanisms of DHA-induced apoptosis in human endometrial cancer cells have not been investigated.
Web11 mrt. 2024 · Findings revealed efficient targeting of the FA- TiO2 NPs resulted in increasing cellular internalization caused increased apoptosis in T24 cells, which might … Web6 apr. 2024 · Alternative strategies using biochemical features of cancer cells to promote apoptosis are finding notable significance. One such important biochemical feature of malignant cells is hypoxia, alteration of which can lead to cell death. Hypoxia inducible factor 1a (HIF-1a) has the key role in hypoxia generation.
Web5 dec. 2013 · Therefore, six most potent extracts (P3-86A, K30, P3-37B, K18, 2 and P3-37C) were also evaluated for apoptosis at 24 h (Figure 1C), and chosen for further investigation to confirm the pathway of induced apoptotic cell death in HeLa cells.
Web4 apr. 2024 · Apoptosis assay Cells were seeded at a density of 1×10 5 cells/well in 24-well plates. After 24 h, cells were treated with FDNVs at concentrations of 25, 50, and … foxridge apartments blacksburg mapWeb1 apr. 1998 · Exposure of H661 cells to 30 microM EGCG, EGC or theaflavins for 24 h led to the induction of apoptosis as determined by an annexin V apoptosis assay, … black white implicit association testWeb28 mei 2004 · Curcumin induced apoptosis in both the lung cancer cell lines. A decrease in expression of p53, bcl-2, and bcl-X L was observed after 12 h exposure of 40 μM curcumin. Bak and Caspase genes remained unchanged up to 60 μM curcumin but showed decrease in expression levels at 80–160 μM. foxridge apartments blacksburg floor plansWeb8 apr. 2024 · SBA-induced cell cycle arrest at G0/G1 phase and increased the apoptotic rates. The Nuclear staining with PI/RNase compound is an indicator for the cell cycle phase. black white indoor seat cushionsWeb1 okt. 2024 · Induction of Apoptosis in SKOV3 cells as a result of treatment with SnO 2 NPs and FA—SnO 2 NPs was studied using acridine orange/ethidium bromide (AO/EB) … black white indian currency 10 rupees imageWeb20 feb. 2013 · Vernodalin inhibited cell growth of human breast cancer cells MCF-7 and MDA-MB-231 by induction of cell cycle arrest and apoptosis. Increased of reactive … black white image to colourWeb3 mei 2024 · By introducing a hydrophobic moiety to the inhibitor structure, we organized a series of degraders of glutathione transferases and demonstrated them potently inducing … fox ridge apartments bowling green ky