Poly rc binding protein 4

WebJul 1, 2024 · Poly(rC)-binding protein 2 (PCBP2) is a member of the poly-cytosine binding protein (PCBP) family, which has been shown to function as regulators in various diseases, including hepatitis C virus infection [2], degenerating neurons [3], acute spinal cord injury [4], and chronic obstructive pulmonary disease [5]. WebIPR033088 Poly(rC)-binding protein 4. Molecular Reagents less. All nucleic 122. cDNA 121. Primer pair 1. Microarray probesets 5. Other Accession IDs less. MGI:1914112 References more. Summaries. All 35. Developmental Gene Expression 3. …

Entry - *608503 - POLY(rC)-BINDING PROTEIN 4; PCBP4 - OMIM

WebHere we discuss recent and old results devoted to type I IRESes and provide evidence that Poly(rC) binding protein 2 (PCBP2), Glycyl-tRNA synthetase (GARS), and Cold Shock Domain Containing E1 (CSDE1, also known as UNR) are major regulators of type I IRES activity. WebNov 1, 2024 · Iron chaperones include the multi-functional poly(rC)-binding proteins 1–4 (PCBPs). • PCBP1/2 play roles in iron metabolism, with the roles of PCBP3/4 being less … sharing shed silverdale https://escocapitalgroup.com

Multilevel regulation and molecular mechanism of poly (rC) …

WebAug 5, 2016 · 4. Discussion. Poly(rC) binding protein 2 (PCBP2, also called hnRNP E2 or α-CP2) belongs to the hnRNP-E family of RNA binding proteins that interact with a sequence-specific motif having single-stranded poly(C) tracts. PCBP2 contains a characteristic triple repeat of heterogeneous nuclear ribonucleoprotein K homology (KH)-domain. WebJul 21, 2015 · In the present study, we specifically examined Poly(rC)-Binding Protein 4 (PCBP4), which reportedly induces G2/M arrest. Results showed that suppression of … WebFind poly a binding protein and related products for scientific research at MilliporeSigma. US EN. Applications Products Services ... Synonym(s): Anti-LIP4, Anti-LYST-interacting protein, Anti-MCG10, Anti-RNA binding protein MCG10, Anti-poly(rC) binding protein 4. Compare Product No. Clonality Application Species Reactivity Citations ... sharing shed takanini

Interaction of poly(rC)-binding protein 2 domains KH1 and KH3 …

Category:57060 - Gene ResultPCBP4 poly(rC) binding protein 4 [ (human)]

Tags:Poly rc binding protein 4

Poly rc binding protein 4

Iron chaperone PCBP1 protects murine liver from lipid

WebOrthologous to several human genes including PCBP2 (poly(rC) binding protein 2). [provided by Alliance of Genome Resources, Apr 2024] pcbp2 poly(rC) binding protein 2 [ (zebrafish)] Gene ID: 321844, updated on 4-Nov-2024. Summary. Enables mRNA 3'-UTR binding activity. Predicted to be ... WebPoly(rC)-Binding Protein 4 (PCBP4) is an RNA-binding protein (RBP). It plays an important role in stabilizing mRNA and translation7,8. The PCBP family consists of hnRNP K, PCBP1, …

Poly rc binding protein 4

Did you know?

WebOct 15, 2024 · Poly (rC)-binding protein 1 (PCBP1), an RNA- or DNA-binding protein with a relative molecular weight of 38 kDa, which is characterized by downregulation in many cancer types. Numerous cases have indicated that PCBP1 could be considered as a tumor suppressor to inhibit tumorigenesis, development, and metastasis. WebNov 14, 2024 · Poly(rC)-binding proteins (PCBPs), a defined subfamily of RNA binding proteins, are characterized by their high affinity and sequence-specific interaction with …

WebRationale: Proper development of the heart relies on a tightly regulated, yet diverse, pattern of gene expression that is governed by transcriptional, post-transcriptional, and translational processe WebNov 1, 2024 · Iron chaperones include the multi-functional poly(rC)-binding proteins 1–4 (PCBPs). • PCBP1/2 play roles in iron metabolism, with the roles of PCBP3/4 being less clear. • The PCBPs bind 3 iron atoms and form hetero/homo dimer complexes. • PCBPs have a subset of non-redundant functions in iron metabolism.

WebFeb 28, 2024 · The cellular RNA-binding protein poly(rC)-18 binding protein 1 (PCBP1) had previously been reported to bind the HCV genome 5´ 19 untranslated region (UTR), but its importance in the viral life cycle has remained unclear. 20 Herein, we aimed to clarify the role of PCBP1 in the HCV life cycle. WebApr 1, 2024 · Download Citation On Apr 1, 2024, Oliveira AG and others published Interaction between poly-A binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response ...

WebNov 4, 2024 · PCBP2 post-transcriptionally regulates sortilin expression by binding to a C-rich element in its 3' UTR. Embryos lacking the KH domain poly (C) binding protein, Pcbp2, are selectively deficient in the definitive erythroid lineage. Compared to wild-type controls, transcript splicing analysis of the Pcbp2 (-/-) embryonic liver reveals accentuated ...

WebOct 16, 2008 · Europe PMC is an archive of life sciences journal literature. Recombinant hnRNP K-homology (KH) domains 1 and 3 of the poly(rC)-binding protein (PCBP) 2 were purified and assayed for interaction with coxsackievirus B3 RNA in electrophoretic mobility shift assays using in vitro transcribed RNAs which represent signal structures of the 5' … sharingshelf.orgWebDec 8, 2024 · Orthologous to human PCBP4 (poly(rC) binding protein 4). [provided by Alliance of Genome Resources, Apr 2024] Other designations. poly(rC)-binding protein 4, … poprow on bing homepageWebSep 22, 2024 · The first pair studied was the protein pair avidin and Biotin. Avidin is a protein typically found in the egg whites while Biotin is a B vitamin. The large protein avidin, can … sharing shed westgateWebPoly(rC)-binding protein 2 is a protein that in humans is encoded by the PCBP2 gene. Function. The protein encoded by this gene appears to be multifunctional. It along with … sharing shelbyWebMar 19, 2024 · Poly(rC)-binding protein1 (PCBP1) is an RNA-binding protein that regulates mRNA stability, splicing, and translation. PCBP1 is a tumor suppressor and can inhibit the translation of several ... sharing shed thursoWebThe cellular protein poly (rC)-binding protein (PCBP) was identified as a primary candidate for regulating such a mechanism. Among the four different isoforms of PCBP in … pop roxx bandWebSep 10, 2009 · Leffers et al. (1995) described the cloning and characterization of 2 cDNAs for poly(rC)-binding proteins, called PCBP1 and PCBP2 (601210) by them. The authors analyzed an EST database for sequences that were predicted to encode a protein with K-homologous (KH) domains. pop rows from dataframe